Artifact Title: The Easter Eggs that accompany most of the Rewinds.Arc Symbol: A special "rewind" version of the YouTube play button, starting with the 2013 rewind.Annual Title: Every video includes the year it was released in the title.This was a reference to the "Screaming Goat" meme, that was also included in the Rewind. Animal Motifs: Goats in the 2013 Rewind they were shown throughout the video, one of the last scenes was a group of people fleeing from a goat stampede, and the Easter Egg sound effect was a goat bleating.until Epic Rap Battles of History pulls the ALS Ice Bucket Challenge on them. Each rewind features songs, celebrities, and cultural references that define that year for the internet. The first rewind came out in December 2010, and a new rewind came out annually up until December 2019. You can find out more about this (and return to this menu) via teneightymagazine.YouTube Rewind was an annual YouTube video series that summarized each year in internet culture. These have caused problems with the stability of the site in the past, so Analytics is necessary for us to keep the site online. It also lets us know how many people are using the site at any given moment, which allows us to identify and deal with traffic spikes. The data collected by Google Analytics is retained indefinitely, but none of it is personally identifiable, and it is not made available to any third parties. We have chosen to use the IP Anonymization option so that your IP address and specific location are never recorded. This helps us learn a bit about who our readers are, what TenEighty content they are interested in, and how they consume it. We use Google Analytics to collect data about (among other things) the pages you view, the device you use to access the site, roughly where you are visiting from, and, if you didn’t come to us directly, the website that linked you to us or the search terms you used to find us. Here’s the full video in case our list wasn’t enough for you (it’s unlikely, we know).ĭo you recognise everyone in it? Who do you think was missing? Let us know via on Twitter or TenEighty UK on Facebook. And that’s basically it! All of this year’s YouTube Rewind summed up in one list without missing a single thing. “This is unbelievably cute.”īut also, here’s a phanfic that contains the line: “…kissing and biting all the way down”. Either way, Alfie, you need to start doing some stretches mate. “OMG it’s a Shia/Sia rap battle!”ĭisappointingly this was not actually the case. They look like they’re desperately trying to be funny but there’s no avoiding the utter misery in their eyes. We hope your family remains well-fed, Pizza Rat. OK, so there is no way to phonetically write out Miranda Sing’s accent but you READ IT IN HER VOICE ANYWAY DON’T DENY IT. (Including a not-so-subtle acknowledgement that YouTube is on an equal footing with TV – YAAAS, go Grace!) 9. If you peer very closely you can just see Left Shark mouthing, “every moment I live is agony” as they’re forced to dance out the side of a vandalised school bus. “Look at the sorrow in Left Shark’s eyes, poor dear.” #HairGoals #StyleGoals #KnitwearGoals #EverythingGoals. “This is honestly the coolest child we have ever seen.” “Hey, they even managed to include the really niche sailing community!” “Only three people chose to board…”Īnd they’re having the most fun EVER. Everybody loves a ball pit. Seriously, we’re getting major cargo ship vibes here. “That is the most inclusive but uninviting cruise liner we’ve ever seen.” It’s not just a skeleton, it’s Lilly Singh, of course! (with OMI’s Cheerleader as the backing track, a perfect example of a song that needs to be eradicated from our lives. Skeletons were clearly the hottest things to come out of 2015, didn’t you know? It’s like YouTube want it to be Halloween all year (IMAGINE). Equality, Whipping and Nae Nae-ing, Mad Max: Fury Road and The Dress are all included in this profound representation of the online world in 2015.Īt nearly 7 minutes in duration, YouTube Rewind: Now Watch Me 2015 is a pretty long video but somehow it managed to keep us occupied. Taking inspiration from all of the major – and, duh, most important – events of the last year, the masterminds at YouTube HQ have once again managed to create a homage to everything we just couldn’t get enough of. Somehow it’s that time again when YouTube wraps up the last 12 months worth of viral, trending and downright weird and wonderful videos into one heaving mass of YouTubers.
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While we were able to find this information by communicating directly with the company, it would be nice to have this information readily available to consumers. Again, Snappy Tom foods are approved by the FDA and the CFIA. This raises a red flag for some pet owners, but Thailand is a major hub for pet food manufacture, so their standards are quite high. Though Snappy Tom does manufacture their products in their own facilities, it’s worth noting that those facilities are located outside the U.S. If you have reservations about cat food made outside the U.S., that should settle the matter for you when it comes to the Snappy Tom brand. As such, their products are approved by both the Canadian Food Inspection Agency (CFIA) and the U.S. Snappy Tom manufactures their products in the same facilities used to process human-grade food. This litter is made from 100% natural, non-toxic plant-based materials that are completely compostable and biodegradable. Snappy Tom plant-based cat litter is available in lavender and vanilla scents as well as an unscented formula. Plus, it’s affordably priced at just $11.99 per 4-pound bag. It is lightweight, non-tracking, and environmentally safe. Snappy Tom crystal cat litter inhibits bacteria and helps keep the litter dry. This litter delivers the convenience of instant odor absorption, enabling you to scoop the box less often. Snappy Tom crystal cat litter comes in two varieties: unscented and lavender scented. Not only does Snappy Tom offer premium-quality cat food, but they also sell two types of cat litter: crystal cat litter and plant-based cat litter. When you choose Snappy Tom, you’re choosing high-quality protein along with perfect taste and an unbeatable texture your cats will love. Here are four promises Snappy Tom makes with each of their products: Snappy Tom “ pride in this distinction and it speaks to the quality and integrity of the products put to market.” Unlike other manufacturers, Snappy Tom doesn’t use by-products, chemicals, fillers, and other ingredients deemed unfit for human consumption. In doing so, they are able to maintain strict quality control over their products every step of the way. This company manufactures their food in company-owned facilities instead of outsourcing production to third-party processors. In addition to setting themselves apart with a unique ingredient, Snappy Tom puts your pet’s health before their bottom line. Today, Snappy Tom proudly makes cat food from “real fish for real cats.” Previously, commercial cat foods largely used beef, chicken, and lamb. Snappy Tom was the first brand in Australia to feature fish as a primary protein source. The story of Snappy Tom began over 50 years ago in Adelaide, Australia. In total, we give Snappy Tom cat food a 48 out of 60 rating or a B grade. A similar post hoc approach as in the “Significant symptoms” section can be found in the “Diagnosis section”. head (27), neck (5), upper arm (3) and chest (8), the papyrus may have guided the differential diagnostic process in those physicians who had the knowledge of the major symptoms of each diagnosis in each region. Nonetheless, since a number of unique cases were documented for most of the regions, i.e. This order of provided information suggests that the documented cases are not chronological descriptions of the diagnostic work-up of an individual case, but rather accurate, post hoc descriptions of the most significant signs and symptoms of the diagnosis under study.Īnother interesting aspect is that none of the cases include differential diagnoses. In line with this “In case of”-approach is the finding that in the “Significant symptoms” section the main diagnosis is always reported prior to the underlying clinical signs and symptoms. This means that other (prognostic) factors than the diagnosis under study were not considered in the treatment decision-making. From another, more modern, point of view the starting fragment may also be interpreted as: “In case of”. From this perspective, one may assume that the cases under study deal with relatively young, healthy male patients. It has been suggested that the cases described in the papyrus predominantly concern patients who sustained their injuries during battles or construction work. Interestingly, no further characteristics of “the man” or cases under study are provided. The “Significant symptoms” section of the cases mostly starts as: “If you examine a man for…”. Most of the cases also include an additional subheading “Explanation” in which unfamiliar terms used in the case description are clarified. Each case includes the following subheadings: “Introductory heading,” “Significant symptoms,” “Diagnosis,” and-if considered treatable-“Recommended treatment”. Besides the mentioned topographic structure of the scroll, all cases are documented in a similar form. The papyrus is astonishingly well structured. This suggests that the writer (or writers) was about to write down more cases dealing with wounds and injuries to the thoracolumbar spine, sacrum and lower limbs. The text of the last case (case 48) comes to an unexpected end in the middle of a sentence. The papyrus includes 48 cases of wounds, injuries and fractures topographically ordered from the skull, neck, upper limbs, chest to the thoracolumbar spine. Before going into detail on the spinal injury cases, it is important to appraise the style and perspective the papyrus was written in. For the clinical appraisal of the spinal injury cases, this latter translation was used for the current review. After thoroughly reinterpreting the original hieratic document, Sanchez and Burridge are currently producing a novel “medically based translation” of the Edwin Smith papyrus. After the publication of his translation in 1930, several other Egyptologists and physicians suggested alternative interpretations of a number of hieroglyphs and fragments written in the original text. Īlthough his translation of the Edwin Smith papyrus is still regarded as a masterpiece, Breasted encountered several problems in his interpretation of the text. Nonetheless, the original authorship remains a controversial issue. and probably is a copy of an older document. A recent reappraisal summarized that the papyrus was most likely penned in the seventeenth century b.c. Breasted suggested that the Egyptian physician Imhotep, who served under the Third Dynasty of pharaoh Djoser (twentysixth century b.c.), could have been the author of the original text. This information led to further speculations on the original authorship. Interestingly, since the hieroglyphics used in the text were more common in earlier times, around 3,000–2,500 b.c., he-and others-believed that the scroll must be a copy of an older text. Based on his vast experience and extensive research, Breasted concluded that the papyrus must have been written during the sixteenth century b.c. There is a need for ways to monitor the status and performance of all the PCs attached to a company’s infrastructure, to ensure they are performing as they should and detect and correct issues before they arise. Of course, such a powerful and essential tool cannot be left unmonitored. From a cashier at the local supermarket to a data analyst at a giant corporation, there are few jobs that do not require the constant use of a PC in some way. Today, in our hyperconnected society, these programs are the cornerstone of the modern workforce. Through the decades, the use cases for PCs in the workplace increased: word processing (WordStar), database management (dBase), design (PageMaker), stock keeping, sales, etc. Needless to say, it opened the doors for competitors like Lotus 1-2-3, on DOS, and eventually Microsoft Excel on Windows. More than 700,000 copies of VisiCalc were sold until 1985, with maybe 1 million copies sold throughout its history. It quickly became the first “killer app”, one so compelling that companies were willing to spend US$2,000 on Apple II computers for their finance and accounting teams, just so they could run VisiCalc, which retailed at US$100. On October 17, 1979, a software publisher called VisiCorp launched a product that would change offices forever: VisiCalc, a spreadsheet program that turned the personal computer (PC) from a mere curiosity into a legitimate business tool. Best hardware monitoring tools compared. Joe Rivkin, who discovered her as a child, saw the cover and cast her in her final film role -her first adult role in a movie- playing a secretary in the suspense drama The Bat with Vincent Price and Agnes Moorehead. In January 1959, Hood released a new record, "My Quiet Village" (Ray Note Records). Between 19 ,she recorded several singles for the small Ray Note and Acama labels. Other credits that year include a hit record, "I Just Wanna Be Free." and a duet with Johnny Desmond in the Sam Katzman movie Calypso Heat Wave. In 1957, Hood was a regular performer on The Merv Griffin Show for the American Broadcasting Network. In 1955, she was a leading lady in the act of ventriloquist Edgar Bergen. She was a regular on The Ken Murray Show from 1950 to 1951. Hood went solo with singing engagements in nightclubs and guest appearances on TV. The group remained with Murray's Blackouts during its long run in New York City and Hollywood. Shortly after graduation, the quintet was booked by producer and vaudeville star Ken Murray for his famous "Blackouts", a stage variety show. While at Fairfax High School, she organized a vocal group called the Enchanters with four boys. When she outgrew her role in Our Gang, Hood appeared in several other movies and attended school in Los Angeles. Hood's final Our Gang appearance was at age 10 in 1941's Wedding Worries. One of her most memorable moments was singing " I'm in the Mood for Love" in The Pinch Singer. She is well remembered for her coquettish character, typically the love interest of Alfalfa, Butch, or (occasionally) Waldo. From 1935 through 1941, she continued to play in Our Gang. She made her debut at age four in the 1935 film Our Gang Follies of 1936 and was soon given a role in The Bohemian Girl with Laurel and Hardy. Hood used her real name in the series except for her debut, in which her character's name was "Cookie". She was then taken to Culver City, California, to appear in the Our Gang series. Just after her third birthday she was taken to New York City, where she was seen by Joe Rivkin, a casting director for Hal Roach Studios, who arranged a screen test. Hood's mother introduced her to singing and dancing at an early age, taking her to lessons in Oklahoma City. She was born in Leedey, Oklahoma, the only child of music teacher Elizabeth Davner, and James Claude Hood, who worked in a bank. Darla Jean Hood (Novem– June 13, 1979) was an American child actress, best known as the leading lady in the Our Gang series from 1935 to 1941. The Cunninghams received additional lands thanks to their support of Robert the Bruce. In the 12th century, the lands of Kilmaurs in Ayrshire were granted to a Norman named Warnebald, whose descendants adopted the territorial name Cunningham. The name derives from the Saxon “cuinneag” meaning “milk pail” along with “ham” meaning “village”. Family motto – Accendit cantu (He excites us with song).Ĭunningham: The family takes its name from the district of Cunningham in Ayrshire. He presided over many of the most important and notorious trials in Victorian England, including the famous Tichborne trial in 1873. Sir Alex J E Cockburn, the eminent Judge, was appointed Solicitor-General in 1850, Chief Justice in 1858 and Lord Chief Justice of England in 1859. The Cockburns were staunch supporters of Mary Queen of Scots, and in 1568 lost their castle at Skirling, in Midlothian as a consequence of this. Sir Alexander’s son, also Sir Alexander, was created Great Usher in the Scots Parliament. Sir Alexander Cockburn de Langton became Keeper of the Great Seal of Scotland in 1390. The surname derives from a place name near Duns, in Berwickshire. Family motto – Fuimus (We have been).Ĭockburn: The Cockburns are a Border Clan. Bruce died at Cardross the following year. Bruce consolidated his kingdom and the war with England was closed by the Treaty of Northampton in 1328. From 1307 he was actively engaged harrying the English, and in 1314 won a decisive victory over Edward II at Bannockburn. In that same year he was defeated at Methven, and took refuge in Rathlin. King Robert the Bruce (1274 – 1329), was crowned King of Scotland in 1306. The Bruces held important lordships in the north of England and a branch of the family settled in Annandale in the 12th century. The name Bruce derives from an area of land in Normandy, France, now called Brix. Family motto – Dominus fecit (God Made).īruce: The Bruces are descended from a Norman Knight who arrived in England with William the Conqueror in 1066. He commanded an expedition to the Cape of Good Hope in 1805. He captured Pondicherry in 1793 and Seringapatam in 1799 and made a famous march across the desert from the Red Sea to the River Nile in 1801. General Sir David Baird (1737 – 1829) entered the Army in 1772 and served in India from 1780 he was severely wounded and taken prisoner by Hyder Ali. John Baird was appointed Lord of Session with the title Lord Newbyth in the 17th century. The Bairds have long been prominent in the legal profession as well as in national affairs. Important families of that name appear from the 14th century. Many of the clans represented have a rich history, such as those featured in our listing below.īaird: From the 13th century this surname has been associated with Lanarkshire and also with the Aberdeen and Banff regions. At the annual Clan Gathering, thousands of people line the Royal Mile to watch the Great Clans of Scotland proudly parading through the ancient streets of the nation’s capital with pipes sounding and drums beating the march. Each year almost 50,000 people from at least 40 countries across the world meet in Scotland’s capital city Edinburgh, to celebrate Scottish culture, heritage and family history. With a user-friendly interface design, this free pdf converter app makes it easy for you to convert photos to pdf. Image to pdf convert easily and safely! You can use a password to protect the pdf with this pdf creator (also can be regarded as a pdf editor). Import images or scan paper files with your camera and convert them to PDFs - notes, receipts, invoices, forms, business cards, certificates, whiteboards, ID cards, etc., all supported. PDF to Image Converter is free and can be used offline.This app basically converts a pdf file into an image. We also provide in the application the feature of adding your own watermark, such as stamping on all files that you convert and use this file in feature. Add, delete,compress pdf file,extract pdf,remove page from pdf ,pdf reorder pages or rotate images.Merge and split PDFs, delete pages, change the page order, and insert blank pages.We're working hard to make this app not only a pdf maker to convert photos to pdf, but also a pdf maker with more features of pdf editor. It can not only convert pictures to pdf convert. You can create text from a qr and barcode scanner into a pdf file.Scan documents, receipts and business cards and Convert them to PDF.Īnyone can easily convert his/her excel file to PDF format.Support xls and csv format to convert PDF format.It is very easy to install and user friendly. You can create a PDF document from a new text document. You can Create Rich Text Note & Convert to PDF file. Want to convert a picture to a pdf? The powerful features make this app an ultimate pdf creator for your device to convert jpg to pdf. It's just one click, and our PDF maker completes your task.In this app you convert text to pdf document. This picture to PDF converter is an impressive image to pdf converter offline that saves you time by simplifying the jpg to PDF process. Now you can convert receipts, personal notes, documents, forms, and many more into a PDF document with this image to pdf converter offline app. With this fantastic jpg to pdf converter app, you can also optimise image size before creating the pdf. Image to pdf! Picture to PDF converter lets you immediately share your PDF to anyone or save it to your phone. Just take a photo with your camera, or choose one from your gallery, and with one click, convert With this image to pdf converter offline app, you can do image to pdf converter offline in just a few minutes. The Motionbox video converter tool is the perfect solution to make your files compatible with what ever device you are trying to upload your video on. Your file might not be supported by the device you are trying to add the file to. If you would like to edit the video, then Motionbox has an awesome video editor for you.ĭepending on your purposes a YouTube file may need to be converted to a mp3 file for compatibility purposes. When it's done you will have a free mp3 file that you can download with no strings attached. This is nice if you need to leave and get a link while on the go. Depending on your settings and the output format it could take a moment.īe patient on this step, you can enter your email if you would like to get a downloadable link when it is ready. Give it a few minutes to convert your YouTube file into mp3 (or which ever formats you have defined). The default will be mp3, but you can change the format on the fly, once you're happy, you can click the convert button. At the top of the metadata you will see a format dropdown button. In a matter of seconds (typically) you will see the video, with it's metadata on the right. Once your YouTube video is uploaded (it doesn't have to be YouTube, we will automatically detect the format if it's different), you will see a progress bar. If your file is not of YouTube type, then the system will automatically detect the file for you. Alternatively you can click the big blue button that says "Upload File". -embed-thumbnail - (Optionally) Embed the video thumbnail into the saved audio files as album art metadata (will be shown in media player applications).Simply drag and drop your YouTube file within the upload zone above.If you do not pass this option, youtube-dl uses a default value of 5, often resulting in lower quality audio than you will get with a value of 0. The possible values here are 0-9 (you can also pass explicit bitrate such as 128K). -audio-quality 0 - Save audio with highest quality possible.-audio-format mp3 - Save the audio stream in mp3 format.-extract-audio - Extract the audio stream and discard the video.-prefer-ffmpeg - Tells youtube-dl to prefer ffmpeg (as opposed to avconv).youtube-dl -prefer-ffmpeg -extract-audio -audio-format mp3 -audio-quality 0 -embed-thumbnail īreaking down the meaning of the supplied options: You can pass it an URL for a single song or even an entire playlist. Youtube-dl -yes-playlist -ignore-errors -sleep-interval 30 -o '%(playlist)s/%(title)s.%(ext)s' "$1"įor this task, I use youtube-dl (w/ a dependency on ffmpeg) with the following options for best results. Youtube-dl -ignore-errors -sleep-interval 30 -i -f bestaudio -extract-audio -audio-format mp3 -audio-quality 0 -o '%(playlist)s/%(playlist_index)s - %(title)s.%(ext)s' "$1" Youtube-dl -ignore-errors -f bestaudio -extract-audio -audio-format mp3 -audio-quality 0 -o '%(title)s.%(ext)s' "$1" This will also help make sure your IP doesn't get banned. It is really simple and also respects YouTube's flood or bot protection by having a 30 second interval between downloads. If I want to download a video as an mp3 I can do that, or download an entire playlist as mp3 I can use mp3p then the url to the playlist. This should honestly just be included aliases when you install the youtube-dl package in my opinion. This question has been answered a lot, but I figured I would add something really useful.
The availability of high-throughput molecular interaction network provides and the application of network analysis tools such as clustering or graph partitioning have proved valuable in disease gene prioritization. Genome-wide association studies and linkage analysis have been pivotal in the identification of candidate genes, however, the large list of resultant genes returned are time-consuming and expensive to analyze. Identification of candidate genes associated with physiological disorders are a fundamental task in the analysis of complex diseases. Research by discovered that genes connected to diseases with similar phenotypes are more likely to interact directly with each other. demonstrated that the majority of disease genes are nonessential and located in the periphery of functional networks. have indicated that the alterations in the physical interaction network may be a indicator of breast cancer prognosis. analyzed topological features of a PPIN and observed that hereditary disease-genes from the Online Mendelian Inheritance in Man (OMIM) database have a larger degree and tendency to interact with other disease-genes in literature curated networks. Network theory is making important contributions to the topological study of biological networks, such as Protein-Protein Interaction Networks (PPIN). Via the analysis of network topology and dynamics, key discoveries have been made including identification of novel disease genes and pathways, biomarkers and drug targets for disease. The emergence of network medicine has explored disease complexity through the systematic identification of disease pathways and modules. The rapid accumulation of high-throughput data along with advances in network biology have been fundamental in improving our knowledge of biological systems and complex disease. This work provides a foundation for future investigation of diverse heterogeneous data integration for disease-gene prioritization. Relatively high predictive performance (AUC: 0.70) was observed when classifying AD and normal gene expression profiles from individuals using leave-one-out cross validation. Biological process enrichment analysis revealed the prioritized genes are modulated in AD pathogenesis including: regulation of neurogenesis and generation of neurons. This approach correctly identified key AD susceptible genes: PSEN1 and TRAF1. The pipeline was applied to prioritize Alzheimer's Disease (AD) genes, whereby a list of 32 prioritized genes was generated. Diverse heterogeneous data including: gene-expression, protein-protein interaction network, ontology-based similarity and topological measures and tissue-specific are integrated. In this paper we propose a computational pipeline for the prioritization of disease-gene candidates. The integration of protein-protein interaction networks along with disease datasets and contextual information is an important tool in unraveling the molecular basis of diseases. The application of gene prioritization can enhance our understanding of disease mechanisms and aid in the discovery of drug targets. An important challenge now is to identify meaningful disease-associated genes from a long list of candidate genes implicated by these analyses. Genome-wide linkage and association studies have made advancements in identifying genetic variants that underpin human disease. The identification of genes and uncovering the role they play in diseases is an important and complex challenge. |
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